Locate Bio
Locate Bio is a regenerative medicine company focused on orthobiologics – biological materials used in orthopedics to promote healing and regeneration of musculoskeletal tissues such as bones, muscles, tendons and ligaments
Regenerative medicine
School of Pharmacy
Profile
Originating from the University of Nottingham’s School of Pharmacy, Locate Bio is a regenerative medicine company focused on orthobiologics – biological materials used in orthopedics to promote healing and regeneration of musculoskeletal tissues such as bones, muscles, tendons and ligaments. Based in Nottingham, the company combines biomaterial design with precision pharmaceutical science to reshape perspectives on recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) and redefine what is possible in bone healing.
At the core of Locate Bio’s pipeline is LDGraft, an investigational bone graft substitute designed to overcome the limitations of earlier biologics. Unlike surface-coated approaches, LDGraft encapsulates rhBMP-2 within a biodegradable polymer. This protects the dose during the inflammatory phase – when rhBMP-2 can cause signal dysregulation – and enables controlled, extended release during the repair phase, when its activity is most beneficial.
Through innovations like LDGraft, Locate Bio is pioneering a new era in orthobiologics, delivering safer, smarter and more effective treatments for patients worldwide.
Our mission is to provide next generation products, both as tools and treatments, that will allow regenerative medicine to realise its potential. Our proprietary TAOS and Intrastem technologies give Locate a unique opportunity to develop and enable the next generation of cellular and gene therapies.
Robin Quirk
Chief Operating Officer
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